Автор: Yashwant Pathak and Deepak Thassu
Название: Drug Delivery Nanoparticles Formulation and Characterization
Издательство: CRC Press
Год: 2009
ISBN: 9781420078046; 1420078046
Серия: Drugs and the Pharmaceutical Sciences (Book 191)
Язык: English
Формат: pdf
Размер: 14,8 mb
Страниц: 416
Drug delivery research is clearly moving from the micro- to the nanosize scale. Nanotechnology is therefore emerging as a field in medicine that is expected to elicit significant therapeutic benefits. The development of effective nanodelivery systems capable of carrying a drug specifically and safely to a desired site of action is one of the most challenging tasks of pharmaceutical formulation investigators. They are attempting to reformulate and add new indications to the existing blockbuster drugs to maintain positive scientific outcomes and therapeutic breakthroughs. The nanodelivery systems mainly include nanoemulsions, lipid or polymeric nanoparticles, and liposomes. Nanoemulsions are primarily used as vehicles of lipophilic drugs following intravenous administration. On the other hand, the ultimate objective of the other nanodelivery systems is to alter the normal biofate of potent drug molecules in the body following their intravenous administration to markedly improve their efficacy and reduce their potential intrinsic severe adverse effects.
The book clearly and comprehensively presents recent advances and knowledge related to formulation and characterization of nanoparticulate drug delivery systems and is an excellent reference for researchers in the field of nanomedicine.