Название: Infection and AutoimmunityАвтор: Shoenfeld Y., Rose N.R.
Издательство: Elsevier
Жанр: Патологическая физиология, Иммунология
Год издания: 2004
Страниц: 768
Язык: Английский
Формат: PDF
Размер: 241 Мб
В настоящем руководстве на основании данных многочисленных фундаментальных исследований и клинических наблюдений раскрывается роль возбудителя инфекции в развитии аутоиммунных заболеваний.
Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
Оглавление
List of Contributors
Introduction: Infection and Autoimmunity
I Mechanisms of Autoimmune Induction by Infection
Implications of T Cell Receptor Crossreactivity for the Pathogenesis of Autoimmune Diseases
Epitope Spreading
Molecular Mimicry in Multiple Sclerosis: Role of MHC-Altered Peptide Ligands (MAPL)
Adverse Events of Desirable Gain in Immunocompetence: The Immune Restoration Inflammatory Syndromes (IRIS)
CD5-Expressing B Cells and Infection
Endothelial Cell Autoreactivity and Infection
II Vaccination
Induction of Autoimmunity by Adjuvant Hydrocarbons
Vaccination and Autoimmunity
BCG Vaccination
III Viruses
Viruses: The Culprits of Autoimmune Diseases?
How Transgenic Mouse Models Contribute to a Better Understanding of Virus-Induced Autoimmunity
Epstein-Barr Virus and Autoimmunity
HIV and Autoimmunity
Parvovirus B19 Infection and Its Association to Autoimmune Disease
Hepatitis C Infection and Vasculitis
HCV and Cryoglobulinemia
Virus-Induced Systemic Vasculitides
Viral Infections and Autoimmune Hepatitis
Viral Infections and Type 1 Diabetes
Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity
Viruses and Multiple Sclerosis
Endogenous Retroviruses as Etiological Agents in Systemic Lupus Erythematosus
Sjogren's Syndrome - Autoimmune Epithelitis: Role of Coxsackieviruses in Pathogenesis
Viral Infection and Heart Disease: Autoimmune Mechanisms
IV Bacteria and Autoimmunity
Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)
Helicobacter Pylori Infection and Gastric Autoimmunity: Coincidence or Cause-Effect Relationship?
Yersinia Enterocolitica Infections and Autoimmune Thyroid Diseases
Reactive Arthritis (Reiter's Syndrome): Roles of Infection, HLA-B27 and the Immune Response
Bovine Spongiform Encephalopathy as an Autoimmune Disease Evoked by Acinetobacter: Implications for Multiple Sclerosis and Creutzfeldt-Jakob Disease
Infection and Autoimmunity in Patients with Antibiotic Treatment-Resistant Lyme Arthritis
Post-Infectious Arthritis: Reactive Arthritis or Slow Infectious Arthritis?
V Parasites and Autoimmunity
Parasitic Infection and Autoimmunity
Autoimmunity in Chagas' Disease
Anti-Saccharomyces Cerevisiae Antibodies and Autoimmune Diseases
VI Infection and Diseases
The Infectious Origin of the Antiphospholipid Syndrome
SLE and Infections
Type I Diabetes Mellitus, Infection and Toll-like Receptors
Infection and Autoimmune Thyroid Diseases
Pemphigus and Infection
Infection, Autoimmunity and Autoimmune Liver Diseases
Infections and Vasculitis
Infection and Multiple Sclerosis
Infections and Polymyositis-Dermatomyositis
Infection and Guillain-Barre Syndrome
Infection and Systemic Sclerosis
Tuberculosis and SLE-like Symptoms as a Complication of Biological Anti-TNF Therapy
Infection and Behcet's Syndrome
Infections and Immune Thrombocytopenic Purpura
Inflammatory Bowel Disease
Infection and Spondyloarthropathies
Celiac Disease and Infection
Infections Associated with Retinal Autoimmunity
Infection and Atherosclerosis
The Pathogenic Role of Heat Shock Proteins in Atherosclerosis
Interaction between Rheumatoid Arthritis and Infections
Subject Index